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Linda Castaldo Selected Research

OSI 930

1/2006OSI-930: a novel selective inhibitor of Kit and kinase insert domain receptor tyrosine kinases with antitumor activity in mouse xenograft models.
8/2005Temporal quantitation of mutant Kit tyrosine kinase signaling attenuated by a novel thiophene kinase inhibitor OSI-930.

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Linda Castaldo Research Topics

Disease

3Neoplasms (Cancer)
10/2012 - 01/2006
1Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung)
10/2012
1Hypertension (High Blood Pressure)
01/2008
1Mast-Cell Leukemia (Leukemia, Mast Cell)
08/2005

Drug/Important Bio-Agent (IBA)

2Proteins (Proteins, Gene)FDA Link
10/2012 - 08/2005
2OSI 930IBA
01/2006 - 08/2005
1rho GTPase-activating proteinIBA
10/2012
1Protein Serine-Threonine Kinases (Protein-Serine-Threonine Kinase)IBA
10/2012
1Monomeric GTP-Binding ProteinsIBA
10/2012
1GTPase-Activating Proteins (GTPase-Activating Protein)IBA
10/2012
1Pharmaceutical PreparationsIBA
01/2008
1Tyrosine (L-Tyrosine)FDA Link
08/2005
1Phosphotransferases (Kinase)IBA
08/2005
1Platelet-Derived Growth Factor Receptors (Platelet-Derived Growth Factor Receptor)IBA
08/2005
1ThiophenesIBA
08/2005